In life, it is inevitable that various problems will cause diseases in the body , and we all know to find some medicine to take. But for men, some drugs are likely to cause damage to sexual function. For example, hormone drugs or some antihypertensive drugs, long-term use will more or less affect the sexual function of men. Therefore, if a man needs to take the following drugs for health reasons, he may wish to consult a doctor first. The following editor will tell you about the medicines that can cause male impotence . If you want to know, you might as well take a look.
drugs that cause impotence
1. Antihypertensive drugs
25% of patients on antihypertensive drugs have impotence, while only 7% of healthy people who do not take drugs have impotence. In addition, 25% of those taking antihypertensive drugs had ejaculation disorders. Reserpine can destroy certain substances in the nerve axis, thereby causing depression in the patient, which in turn affects the patient’s sexual desire or erection difficulties. Guanethidine directly counteracts the effects of the sympathetic nerves, so impotence and ejaculation difficulties are common. On the one hand, clonidine inhibits the sympathetic nerve function, and on the other hand, it can cause depression, so it is easy to cause sexual dysfunction .
After taking propranolol for a long time, the blood vessels of the cavernous body of the penis contract and the blood flow decreases due to blocking the adrenergic nerve activity, which eventually leads to impotence.
1. Adrenal cortex hormones: such as prednisone and dexamethasone, are used to treat immune infertility with antisperm antibodies to suppress the patient’s immune response, but when the daily dosage reaches 20 mg, sex can occur Dysfunction. In addition, long-term use of such drugs can also induce diabetes, high blood pressure, and obesity.
2. Estrogen: It is often used clinically to treat benign prostatic hyperplasia. These patients will have obvious side effects such as male breast hyperplasia, beard growth reduction and slowdown, loss of libido, impotence, ejaculation disorder, and semen volume reduction.
3. Cyproterone: It is a synthetic steroidal compound with anti-androgen activity, which plays a competitive inhibitory role in androgen target organs. During the period of medication, it can lead to disorder of the reproductive endocrine axis system. Symptoms such as loss of libido, weak erection, and impotence can be seen in about a week. Long-term use can lead to infertility due to low sperm count.
4. Testosterone: A large amount of external testosterone inhibits the endocrine function of the pituitary gland and testis, reducing the secretion of endogenous testosterone, especially those patients with psychological impotence who do not lack testosterone, but interfere with normal metabolism and endocrine function after medication.
For example, spironolactone is an aldosterone-resistant drug, which can inhibit the activity of testosterone synthase, reduce testosterone synthesis, and lower blood levels. It can cause 20% of men to experience loss of libido. In addition, diuretics can cause potassium loss in the body, decrease blood potassium concentration, reduce neuromuscular sensitivity, relax vascular smooth muscle, and lead to weakened penile erection.
Large doses of diazepam directly have a specific effect on the limbic system of the brain, directly reducing or enhancing libido function. Stability, etc. have the effect of relaxing muscles, and can cause loss of libido and impotence through the efferent nerves of the spinal cord.
5. Antipsychotic drugs
Some drugs can paralyze the seminal vesicle and ejaculate, and some drugs can lead to a decrease in testosterone levels and sperm production disorders. The depression drug amitriptyline and doxepin can inhibit the action of α-adrenergic nerves and make the blood flow of the cavernous body of the penis disappear, delay and delay, so some people use it to treat premature ejaculation, but the blood vessels caused by long-term large-scale use are common Contraction can make the penis weak to erect, leading to impotence.